SML0126
OBA-09 hydrate
≥98% (HPLC)
别名:
2-(1,2-Dioxopropoxy)benzoic acid hydrate, O-Pyruvoylsalicylic acid hydrate
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关于此项目
经验公式（希尔记法）:
C10H8O5 · xH2O
化学文摘社编号:
分子量:
208.17 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
SMILES string
O.CC(=O)C(=O)Oc1ccccc1C(O)=O
InChI
1S/C10H8O5.H2O/c1-6(11)10(14)15-8-5-3-2-4-7(8)9(12)13;/h2-5H,1H3,(H,12,13);1H2
InChI key
DLKFQAHWYMEWIK-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥24 mg/mL
storage temp.
2-8°C
Application
OBA-09 hydrate may be used in cell signaling studies.
Biochem/physiol Actions
Neuroprotective agent
OBA-09 is a neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ischemic damages to the brain. Administration of 5 mpk OBA-09 following middle cerebral artery occlusion (MCAO) or oxygen-glucose deprivation (OGD) models of ischemic injury in rats prevents lipid peroxidation, ROS production and causes the recovery of NAD and ATP concentrations to near basal levels. The compound leads to reduction of infarct volume and also accelerates the recovery of behavioral and neurological deficits.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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