SML0215
5(S),6(R),7-Trihydroxyheptanoic acid methyl ester
≥98% (HPLC)
别名:
BML 111
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关于此项目
经验公式（希尔记法）:
C8H16O5
化学文摘社编号:
分子量:
192.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C8H16O5/c1-13-8(12)4-2-3-6(10)7(11)5-9/h6-7,9-11H,2-5H2,1H3/t6-,7+/m0/s1
SMILES string
COC(=O)CCC[C@H](O)[C@H](O)CO
InChI key
RNMFWAFZUNVQOR-NKWVEPMBSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: ≥20 mg/mL
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
5(S),6(R),7-Trihydroxyheptanoic acid methyl ester may be used in lipoxin A receptor-mediated cell signaling studies.
Biochem/physiol Actions
5(S),6(R),7-Trihydroxyheptanoic acid methyl ester is a FRP2/ALX agonist
BML-111 is an analog of the naturally occurring eicosanoid Lipoxin A4. It is an agonist of lipoxin A receptor, also known as formyl peptide receptor 2 (ALX or FPR2). BML-111 potently inhibits cytokine expression and inflammatory cell infiltration in rodent arthritis models, and blocks angiogenesis and tumor growth in hepatic tumor models.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Xia Kong et al.
Experimental and therapeutic medicine, 14(3), 2284-2290 (2017-10-01)
Previous studies have demonstrated that lipoxin A
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