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经验公式(希尔记法):
C16H13N5O2S
化学文摘社编号:
分子量:
339.37
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C16H13N5O2S/c1-22-12-7-6-10(9-13(12)23-2)15-20-21-14(18-19-16(21)24-15)11-5-3-4-8-17-11/h3-9H,1-2H3
SMILES string
COc1ccc(cc1OC)-c2nn3c(nnc3s2)-c4ccccn4
InChI key
MEWRLQUBVOVSGN-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL (clear solution; warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Cardionogen-2 is a biphasic modulator of cardiogenesis that enlarges the size of the zebrafish embryonic heart by promoting cardiomyocyte formation. Also, cardionogen-2 promotes murine ES cells to differentiate into beating cardiomyocytes. Apparently, cardionogen-2 inhibits Wnt/b-catenin dependent transcriptional activity. Treatment of zebrafish embryos with cardionogen-2 significantly enlarged both the atrium and ventricle, without causing apparent defects of embryonic morphology or other organ development.
Cardionogen-2 is a biphasic modulator of cardiogenesis; inhibits Wnt/β-catenin dependent transcriptional activity.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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