SML0456
HBB2
≥98% (HPLC)
别名:
(1E,4E)-1,5-Bis(2-Hydroxyphenyl)-1,4-pentadien-3-one
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C17H14O3
化学文摘社编号:
分子量:
266.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL (clear solution)
storage temp.
−20°C
SMILES string
Oc1ccccc1\C=C\C(=O)\C=C\c2ccccc2O
InChI
1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12,19-20H/b11-9+,12-10+
InChI key
YNVAHBUBGBLIEY-WGDLNXRISA-N
Biochem/physiol Actions
HBB2 is an inducer of the KEAP1/NRF2/ARE pathway that reacts with sulfhydryl groups. Also, HBB2 upregulates Hsp70 in an HSF1-dependent manner. It appears that HBB2 reacts with cysteine residues of KEAP1, which leads to activation of NRF2, and binds to Hsp90 Cys that leads to activation of HST1.
HBB2 is an inducer of the KEAP1/NRF2/ARE pathway, and upregulator of Hsp70.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Tae Hyun Kim et al.
PloS one, 10(7), e0133450-e0133450 (2015-07-18)
In order to develop novel strategies to protect against increasingly virulent bird-linked pathogens, a better understanding of the avian antiviral response mechanism is essential. Type I interferons (IFNs) are recognized as the first line of defense in a host's antiviral
Mohamad Toutounji et al.
International journal of molecular sciences, 21(8) (2020-04-25)
A key morphological feature of inflammatory bowel disease (IBD) is the loss of the barrier function of intestinal epithelial cells. The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML0456-5MG | 04061832633503 |
| SML0456-25MG | 04061832633497 |