SML0457
AE9C90CB
≥98% (HPLC)
别名:
N-[(1a,5a,6a)-3-Azabicyclo[3.1.0]hex-6-ylmethyl]-a-hydroxy-N-methyl-a-phenyl-benzeneacetamide hydrochloride (1:1)
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
H2O: 15 mg/mL (clear solution)
储存温度
2-8°C
SMILES字符串
Cl.CN(C[C@@H]1[C@H]2CNC[C@@H]12)C(=O)C(O)(c3ccccc3)c4ccccc4
InChI
1S/C21H24N2O2.ClH/c1-23(14-19-17-12-22-13-18(17)19)20(24)21(25,15-8-4-2-5-9-15)16-10-6-3-7-11-16;/h2-11,17-19,22,25H,12-14H2,1H3;1H/t17-,18+,19+;
InChI key
YHBAWCACDJQGDL-MSFHQNQXSA-N
生化/生理作用
AE9C90CB is a muscarinic acetylcholine receptor antagonist with 20-fold selectivity for M3 receptor subtypes compared to M2. In an in vivo assay, AE9C90CB was approximately 5 times more selective for inhibiting carbachol-induced urinary bladder contraction, compared to saliva production.
AE9C90CB is a tissue specific M3 muscarinic receptor antagonist.
特点和优势
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
商品
Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.
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