SML0458
Cardionogen-1
≥98% (HPLC)
别名:
6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, CDNG1, Cardionogen-1/vuc230
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关于此项目
经验公式（希尔记法）:
C13H14N4OS
化学文摘社编号:
分子量:
274.34
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL (clear solution)
储存温度
2-8°C
SMILES字符串
C1CCC(CC1)c2nn3c(nnc3s2)-c4ccco4
InChI
1S/C13H14N4OS/c1-2-5-9(6-3-1)12-16-17-11(10-7-4-8-18-10)14-15-13(17)19-12/h4,7-9H,1-3,5-6H2
InChI key
SWTUPSNBTSPBIH-UHFFFAOYSA-N
生化/生理作用
Cardionogen-1 is cardiomyocyte promoter and an inhibitor of Wnt/β-catenin dependent transcription.
Cardionogen-1 is cardiomyocyte promoter and an inhibitor of Wnt/β-catenin dependent transcriptional activity with an EC50 of 23 nM in murine stem cells and zebrafish embryos. It induces cardiac cell formation in both murine stem cells and zebrafish embryos, expanding cardiac progenitor cells.
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