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Merck
CN

SML0463

BPD

≥98% (HPLC)

别名:

3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione

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关于此项目

经验公式(希尔记法):
C17H10O5
化学文摘社编号:
分子量:
294.26
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

−20°C

SMILES string

O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4

InChI

1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2

InChI key

IMHGOAWBSJVILI-UHFFFAOYSA-N

Biochem/physiol Actions

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.
BPD inhibits LPS-induced NF-kB signaling; COX-2 inhibitor.

Features and Benefits

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

pcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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Anna Karin Edstedt Bonamy et al.
Archives of disease in childhood. Fetal and neonatal edition, 104(1), F36-F45 (2018-01-22)
To investigate the variation in severe neonatal morbidity among very preterm (VPT) infants across European regions and whether morbidity rates are higher in regions with low compared with high mortality rates. Area-based cohort study of all births before 32 weeks
Sebastian Euler et al.
Frontiers in psychology, 9, 824-824 (2018-06-19)
Interpersonal sensitivity, particularly threat of potential exclusion, is a critical condition in borderline personality disorder (BPD) which impairs patients' social adjustment. Current evidence-based treatments include group components, such as mentalization-based group therapy (MBT-G), in order to improve interpersonal functioning. These
Jennifer Sophie Landry et al.
Annals of the American Thoracic Society, 13(1), 17-24 (2015-11-03)
Bronchopulmonary dysplasia and the long-term consequences of prematurity are underrecognized entities, unfamiliar to adult clinicians. Well described by the pediatric community, these young adults are joining the ranks of a growing population of adults with chronic lung disease. To describe
Graciela Sotelo et al.
BMC evolutionary biology, 20(1), 23-23 (2020-02-11)
The flat periwinkles, Littorina fabalis and L. obtusata, are two sister species widely distributed throughout the Northern Atlantic shores with high potential to inform us about the process of ecological speciation in the intertidal. However, whether gene flow has occurred
Carla Sharp et al.
Assessment, 26(6), 1014-1029 (2018-07-14)
DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) Section II criteria for borderline personality disorder (BPD) lack developmental operationalization. The aim of the current study was to evaluate whether DSM criteria operate similarly across adolescents and adults to

全球贸易项目编号

货号GTIN
SML0463-25MG04061832261218
SML0463-5MG04061832786599

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