SML0490
DDN
≥98% (HPLC)
别名:
2,3-Dichloro-naphthazarin diacetate, 5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone, 5,8-bis(acetyloxy)-2,3-dichloro-1,4-naphthalenedione
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关于此项目
经验公式（希尔记法）:
C14H8Cl2O6
化学文摘社编号:
分子量:
343.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C14H8Cl2O6/c1-5(17)21-7-3-4-8(22-6(2)18)10-9(7)13(19)11(15)12(16)14(10)20/h3-4H,1-2H3
SMILES string
O=C1C(Cl)=C(Cl)C(C2=C1C(OC(C)=O)=CC=C2OC(C)=O)=O
InChI key
QIJKSJNUTOPANC-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
light orange to dark orange
solubility
DMSO: 2 mg/mL (clear solution, warmed)
storage temp.
2-8°C
Biochem/physiol Actions
DDN (5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone) is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain and induces the Akt and ERK phosphorylations. DDN also improves glucose uptake in adipocytes and produces oral hypoglycemic effect in wild-type and diabetic mice models.
DDN is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain; functional insulin mimetics
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
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