SML0490
DDN
≥98% (HPLC)
别名:
2,3-Dichloro-naphthazarin diacetate, 5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone, 5,8-bis(acetyloxy)-2,3-dichloro-1,4-naphthalenedione
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关于此项目
经验公式(希尔记法):
C14H8Cl2O6
化学文摘社编号:
分子量:
343.12
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
颜色
light orange to dark orange
溶解性
DMSO: 2 mg/mL (clear solution, warmed)
储存温度
2-8°C
SMILES字符串
O=C1C(Cl)=C(Cl)C(C2=C1C(OC(C)=O)=CC=C2OC(C)=O)=O
InChI
1S/C14H8Cl2O6/c1-5(17)21-7-3-4-8(22-6(2)18)10-9(7)13(19)11(15)12(16)14(10)20/h3-4H,1-2H3
InChI key
QIJKSJNUTOPANC-UHFFFAOYSA-N
生化/生理作用
DDN (5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone) is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain and induces the Akt and ERK phosphorylations. DDN also improves glucose uptake in adipocytes and produces oral hypoglycemic effect in wild-type and diabetic mice models.
DDN is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain; functional insulin mimetics
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
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