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Merck
CN

SML0490

Sigma-Aldrich

DDN

≥98% (HPLC)

别名:

2,3-Dichloro-naphthazarin diacetate, 5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone, 5,8-bis(acetyloxy)-2,3-dichloro-1,4-naphthalenedione

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关于此项目

经验公式(希尔记法):
C14H8Cl2O6
化学文摘社编号:
分子量:
343.12
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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方案

≥98% (HPLC)

表单

powder

颜色

light orange to dark orange

溶解性

DMSO: 2 mg/mL (clear solution, warmed)

储存温度

2-8°C

SMILES字符串

O=C1C(Cl)=C(Cl)C(C2=C1C(OC(C)=O)=CC=C2OC(C)=O)=O

InChI

1S/C14H8Cl2O6/c1-5(17)21-7-3-4-8(22-6(2)18)10-9(7)13(19)11(15)12(16)14(10)20/h3-4H,1-2H3

InChI key

QIJKSJNUTOPANC-UHFFFAOYSA-N

生化/生理作用

DDN (5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquinone) is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain and induces the Akt and ERK phosphorylations. DDN also improves glucose uptake in adipocytes and produces oral hypoglycemic effect in wild-type and diabetic mice models.
DDN is a selective insulin receptor (IR) activator that binds directly to the receptor kinase domain; functional insulin mimetics

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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分析证书(COA)

Lot/Batch Number

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