羟基保泰松

Name: 羟基保泰松
Brand: SIGMA

≥98% (HPLC)

别名:

4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione, G 27202, NSC 526053, Ro 04-4410, p-Hydroxyphenylbutazone, p-Oxyphenylbutazone

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₉H₂₀N₂O₃

CAS Number:

129-20-4

分子量:

324.37

UNSPSC代码:

12352200

NACRES:

NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to brown

溶解性

DMSO: 10 mg/mL, clear

储存温度

−20°C

SMILES字符串

N2(N(C(=O)C(C2=O)CCCC)c3ccccc3)c1ccc(cc1)O

InChI

1S/C19H20N2O3/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15/h4-8,10-13,17,22H,2-3,9H2,1H3

InChI key

HFHZKZSRXITVMK-UHFFFAOYSA-N

一般描述

Oxyphenbutazone is a derivative compound of phenylbutazone.

生化/生理作用

Oxyphenbutazone is a non-steroid anti inflammatory; anti Mycobacterium tuberculosis agent.

Oxyphenbutazone is a non-steroid anti inflammatory; anti Mycobacterium tuberculosis agent. Oxyphenbutazone is known to cause inflammatory effects on tissues. Oxyphenbutazone, as a drug, decreases cellular exudates, without involving the pituitary-adrenal axis or the immunity response. Though the drug delivers a number of side effects, it is considered to be less toxic than phenylbutazone, due to decreased rate of intestinal absorption.

Oxyphenbutazone is an NSAID that has been shown to preferentially kill non-replicating Mycobaterium tuberculosis maintained in media that simulates the mildly acidic, in vivo conditions where drug-resistant, non replicating subpopulations of the bacteria reside in hosts. The compound has little or no affect on replication M. tuberculosis grown in normal liquid cultures.