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Merck
CN

SML0600

LPSF/GQ-02

≥98% (HPLC)

别名:

(5Z)-5-[(4-Chlorophenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione, 5-(4-Chloro-benzylidene)-3-(4-methyl-benzyl)-thiazolidine-2,4-dione, GQ-02

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关于此项目

经验公式(希尔记法):
C18H14ClNO2S
化学文摘社编号:
分子量:
343.83
NACRES:
NA.77
UNSPSC Code:
12352202
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

LPSF/GQ-02 is a new thiazolidinedione that shows improved insulin resistance, reduces the area of atherosclerotic lesions, and offers a protective effect for the endothelium in LDL receptor-deficient mice.
LPSF/GQ-02 is a new thiazolidinedione that shows improved insulin resistance, reduces the area of atherosclerotic lesions, and offers a protective effect for the endothelium in LDL receptor-deficient mice. LPSF/GQ-02 induced an overexpression of eNOS and significantly inhibited the expression of metalloproteinases, both of which can result in anti-inflammatory effects.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors related to hormone receptors, influencing gene expression.

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