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Merck
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SML0689

Anatabine

≥95% (HPLC)

别名:

(RS)-Anatabine, (±)-Anatabine, 1,2,3,6-Tetrahydro-2,3′-bipyridine, 1,2,3,6-Tetrahydro-2,3′-dipyridine

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关于此项目

经验公式（希尔记法）:
C10H12N2
化学文摘社编号:
2743-90-0
分子量:
160.22
UNSPSC Code:
12352200
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assay

≥95% (HPLC)

form

oil

color

colorless to light brown

storage temp.

−20°C

InChI

1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2

InChI key

SOPPBXUYQGUQHE-UHFFFAOYSA-N

Biochem/physiol Actions

Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties.
Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties. Apparently, anti-inflammatory properties of anatabine are partially mediated by inhibition of STAT3 and p65 NFkB phosphorylation. Anatabine decreases the transcription and protein synthesis of β-secretase (BACE-1), and appears to ameliorate experimental autoimmune thyroiditis and encephalomyelitis.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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