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Merck
CN

SML0722

CU-CPT22

≥98% (HPLC)

别名:

5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

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关于此项目

经验公式(希尔记法):
C19H22O7
化学文摘社编号:
分子量:
362.37
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C19H22O7/c1-3-4-5-6-7-26-19(24)12-8-11-10-14(25-2)17(22)18(23)15(11)16(21)13(20)9-12/h8-10,22-23H,3-7H2,1-2H3,(H,20,21)

SMILES string

OC1=C(O)C(OC)=CC2=C1C(C(O)=CC(C(OCCCCCC)=O)=C2)=O

InChI key

UBQFTTUFRSSOHE-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

orange to dark red

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2.
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2.

pictograms

Health hazardEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yuming Zhang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(2), 827-837 (2018-07-23)
Dairy cows with clinical ketosis display a negative energy balance and high blood concentrations of non-esterified fatty acids (NEFAs), the latter of which is an important pathological factor of ketosis in cows. The aims of this study were to investigate
Stephanie Bock et al.
Pharmacological research, 105, 44-53 (2016-01-23)
Langerhans cells (LCs) represent a highly specialized subset of epidermal dendritic cells (DCs), yet not fully understood in their function of balancing skin immunity. Here, we investigated in vitro generated Langerhans-like cells obtained from the human acute myeloid leukaemia cell
Rafael M Rezende et al.
Nature communications, 9(1), 3151-3151 (2018-08-10)
γδ T cells have many known functions, including the regulation of antibody responses. However, how γδ T cells control humoral immunity remains elusive. Here we show that complete Freund's adjuvant (CFA), but not alum, immunization induces a subpopulation of CXCR5-expressing
Qi Su et al.
International journal of medical microbiology : IJMM, 307(2), 108-112 (2016-12-28)
Propionibacterium acnes has been considered as a crucial contributor to the pathogenesis of acne vulgaris. The interaction between P. acnes and the host is mainly mediated by Toll like receptor (TLR) 2 recognition. TLR2 homodimers recognize P. acnes in mice
Jieun Kim et al.
Nutrients, 10(7) (2018-07-07)
Toll-like receptor 2 (TLR2) responses are involved in various inflammatory immune disorders. Phloretin is a naturally occurring dietary flavonoid that is abundant in fruit. Here, we investigated whether the anti-inflammatory activity of phloretin is mediated through TLR2 pathways, and whether

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