SML0787
AC 42
≥98% (HPLC)
别名:
4-(4-Butyl-1-piperidinyl)-1-(2-methylphenyl)-1-butanone hydrochloride, AC-42
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 5 mg/mL, clear (warmed)
储存温度
−20°C
SMILES字符串
Cl.N2(CCC(CC2)CCCC)CCCC(=O)c1c(cccc1)C
InChI
1S/C20H31NO.ClH/c1-3-4-9-18-12-15-21(16-13-18)14-7-11-20(22)19-10-6-5-8-17(19)2;/h5-6,8,10,18H,3-4,7,9,11-16H2,1-2H3;1H
InChI key
HJCOVULGUXGGSU-UHFFFAOYSA-N
生化/生理作用
AC-42 is a specific agonist of the muscarininc M1 receptor (pEC50 = 6.54) with little or no activity against other muscarinic receptor family members. AC-42 binds to an allosteric site adjacent to the adjacent to the orthosteric, acetylcholine binding site.
AC-42 is a specific agonist of the muscarininc M1 receptor.
特点和优势
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Beatrice Mihaela Radu et al.
Scientific reports, 7(1), 5083-5083 (2017-07-13)
Clinical and experimental studies indicate that muscarinic acetylcholine receptors are potential pharmacological targets for the treatment of neurological diseases. Although these receptors have been described in human, bovine and rat cerebral microvascular tissue, a subtype functional characterization in mouse brain
商品
DISCOVER Bioactive Small Molecules for Neuroscience
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持