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About This Item
经验公式（希尔记法）:
C12H16N2
CAS Number:
分子量:
188.27
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.77
Product Name
N,N-二甲基色胺, ≥97% (HPLC)
质量水平
方案
≥97% (HPLC)
表单
powder
药品控制
USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
颜色
white to beige
溶解性
DMSO: 15 mg/mL, clear
储存温度
−20°C
SMILES字符串
CN(C)CCC1=CNC2=C1C=CC=C2
InChI
1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3
InChI key
DMULVCHRPCFFGV-UHFFFAOYSA-N
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生化/生理作用
N,N-Dimethyltryptamine (DMT) functions as a hallucinogen. Experimental studies states that DMT is an endogenous sigma-1 receptor agonist. DMT interacts with sigma-1 receptors and blocks voltage-gated sodium ion (Na+) channels in both native cardiac myocytes and heterologous cells that contain sigma-1 receptors.
N,N-Dimethyltryptamine (DMT) is a hallucinogen now known to be an endogenous sigma-1 receptor agonist. In keeping with the known sigma-1 receptor modulation of voltage gated Na+ channels, DMT was found to reversibly inhibit Na currents by 62% in vitro. N,N-Dimethyltryptamine also induced hypermotility in WT mice (but not in sigma-1 KO mice), all evidence of its sigma-1 agonist activity.
N,N-Dimethyltryptamine is an endogenous sigma-1 receptor agonist; hallucinogen.
特点和优势
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
其他说明
Product contains 1.2% wt. EtOH (by NMR and EA).
警示用语：
Warning
危险声明
危险分类
STOT SE 3
靶器官
Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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