SML1021
BC-1258
别名:
N,N′-Bis-(4-thiazol-2-yl-benzyl)-ethane-1,2-diamine
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C22H22N4S2
化学文摘社编号:
分子量:
406.57
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
C1(C2=NC=CS2)=CC=C(CNCCNCC3=CC=C(C4=NC=CS4)C=C3)C=C1
InChI
1S/C22H22N4S2/c1-5-19(21-25-11-13-27-21)6-2-17(1)15-23-9-10-24-16-18-3-7-20(8-4-18)22-26-12-14-28-22/h1-8,11-14,23-24H,9-10,15-16H2
InChI key
FRTSLZJCGAFSET-UHFFFAOYSA-N
Biochem/physiol Actions
BC-1258 is a potent activator of unique E3 ligase F-box/LRR-repeat protein 2 (FBXL2) that increases levels of FBXLs protein, thus promoting Aurora B degradation. BC-1258 induces mitotic arrest and apoptosis of tumorigenic cells. Also BC-1258 inhibits tumor formation in athymic nude mice.
BC-1258 is a potent activator of unique E3 ligase F-box/LRR-repeat protein 2 (FBXL2).
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML1021-25MG | 04061833224649 |
| SML1021-5MG | 04061833224656 |