SML1036
LDN-193594
≥98% (HPLC)
别名:
[4-Amino-2-(3-pyridinylamino)-5-thiazolyl](2-fluorophenyl)-methanone
InChI
1S/C15H11FN4OS/c16-11-6-2-1-5-10(11)12(21)13-14(17)20-15(22-13)19-9-4-3-7-18-8-9/h1-8H,17H2,(H,19,20)
InChI key
XHJMMMPXTUEBMQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
LDN-193594 is a potent and nontoxic dual inhibitor of CDK5/p25 and GSK3β that reduces tau protein phosphorylation and exerts neuroprotective effects in vivo. LDN-193594 improves the tauopathy in mice models.
LDN-193594 is a potent and nontoxic dual inhibitor of CDK5/p25 and GSK3β.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4 - Eye Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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