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Merck
CN

SML1328

AZ20

≥98% (HPLC)

别名:

4{4-[(3R)3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}1Hindole

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关于此项目

经验公式(希尔记法):
C21H24N4O3S
化学文摘社编号:
分子量:
412.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CS(C1(CC1)C2=CC(N3[C@H](C)COCC3)=NC(C4=CC=CC5=C4C=CN5)=N2)(=O)=O

InChI

1S/C21H24N4O3S/c1-14-13-28-11-10-25(14)19-12-18(21(7-8-21)29(2,26)27)23-20(24-19)16-4-3-5-17-15(16)6-9-22-17/h3-6,9,12,14,22H,7-8,10-11,13H2,1-2H3/t14-/m1/s1

InChI key

SCGCBAAYLFTIJU-CQSZACIVSA-N

Biochem/physiol Actions

AZ20 is cell penetrant potent and selective ATR (ataxia telangiectasia and Rad3-related protein) kinase inhibitor that potently inhibits the growth of LoVo colorectal adenocarcinoma xenografts in mice.
AZ20 is cell penetrant potent and selective ATR kinase inhibitor.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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全球贸易项目编号

货号GTIN
SML1328-5MG04061833026014
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