SML1361
BRD73954
≥98% (HPLC)
别名:
N-Hydroxy-N′-phenethyl-isophthalamide, N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide, N1-Hydroxy-N3-phenethylisophthalamide
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关于此项目
经验公式（希尔记法）:
C16H16N2O3
化学文摘社编号:
分子量:
284.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
InChI
1S/C16H16N2O3/c19-15(17-10-9-12-5-2-1-3-6-12)13-7-4-8-14(11-13)16(20)18-21/h1-8,11,21H,9-10H2,(H,17,19)(H,18,20)
SMILES string
ONC(C1=CC(C(NCCC2=CC=CC=C2)=O)=CC=C1)=O
InChI key
FIHKWEQJEDRIFS-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to light brown
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
BRD73954 is the first discovered histone deacetylase 6/8 dual inhibitor.
BRD73954 is the first discovered histone deacetylase 6/8 dual inhibitor. BRD73954 has an IC50 of 36 nM for the class IIb HDAC6 and 120 nM for the class I HDAC8 with IC450′s ranging from 9 μM to greater than 33 μM for other HDACs.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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