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经验公式(希尔记法):
C17H19N7O5S3
化学文摘社编号:
分子量:
497.57
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI
1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1
SMILES string
O=C(N[C@H](C(O)=O)CCCNC(N)=N)C1=C(C=CS1)NS(C2=CC=CC3=NSN=C32)(=O)=O
InChI key
ZWWMEDURALZMEV-NSHDSACASA-N
assay
≥98% (HPLC)
form
powder
color
, pale yellow to yellow-orange
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
EG00229 is an antagonist of the VEGF-A receptor neuropilin 1 (NRP1), which decreases viability of A549 lung carcinoma cells. EG00229 impairs VEGFA induced migration of HUV-EC-C endothelial cells.
EG00229 is an antagonist of the VEGF-A receptor neuropilin 1 (NRP1).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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