SML1675
SKY Peptide trifluoroacetate salt
≥98% (HPLC)
别名:
L-Arginyl-L-arginyl-L-tyrosylglycyl-L-threonyl-L-seryl-L-lysyl-L-tyrosyl-L-glutamine TFA salt, RRYGTSKYQ
方案
≥98% (HPLC)
表单
powder
颜色
white to off-white
运输
wet ice
储存温度
−20°C
生化/生理作用
SKY Peptide is a non-cytotoxic and stable nonapeptide modeled after human neutrophil peptide 1 (HNP1, a-defensin) β strand 2 CCL5-binding mode to optimally complete against HNP1 for CCL5 interaction (EC50 ~ 0.1 μg/mL against 10 μg/mL HNP1 and 1 μg/mL CCL5 heteromer formation on HUVECs) without affecting CCL5 and cell surface CCR5 interaction. SKY Peptide is shown to inhibit HNP1-CCL5 heteromer-dependent classical monocytes adhesion both in cultures in vitro (EC50 <1 μg/mL; 10 μg/mL HNP1 and 1 μg/mL CCL5 over HUVEC monolayer) and in mice in vivo.
SKY Peptide is a non-cytotoxic and stable nonapeptide.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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