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Merck
CN

SML1754

CTX1

≥95% (HPLC)

别名:

3,6-Diamino-9-acridinecarbonitrile, NSC 363260

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关于此项目

经验公式(希尔记法):
C14H10N4
化学文摘社编号:
分子量:
234.26
NACRES:
NA.77
UNSPSC Code:
12352200
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assay

≥95% (HPLC)

form

powder

color

, faint to very dark red

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

CTX1 is a potent HdmX inhibitor that overcomes HdmX-mediated p53 repression.
CTX1 is a potent HdmX inhibitor that overcomes HdmX-mediated p53 repression. CTX1 inhibits proliferation and induces apoptosis in number of cancer cell lines. CTX1 inhibits growth of primary human AML in immunodeficient mice.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hong Han et al.
Experimental and therapeutic medicine, 22(6), 1457-1457 (2021-11-06)
Skeletal muscle injury is one of the most common sports injury, which accounts for ~40% of all sports-related injuries among the elderly. In addition, cases of full recovery from treatment are rare. Although electroacupuncture (EA) is an integral aspect of
Goutam Karan et al.
Molecular cancer therapeutics, 15(4), 574-582 (2016-02-18)
Inactivation of the p53 tumor suppressor by mutation or overexpression of negative regulators occurs frequently in cancer. As p53 plays a key role in regulating proliferation or apoptosis in response to DNA-damaging chemotherapies, strategies aimed at reactivating p53 are increasingly

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