SML2329
RP22
≥98% (HPLC)
别名:
AA147 Inactive Control, AA147 Negative Control, N-(2-Hydroxy-5-(trifluoromethyl)phenyl)-3-phenylpropanamide, N-[2-hydroxy-5-(trifluoromethyl)phenyl]-benzenepropanamide
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O=C(NC1=CC(C(F)(F)F)=CC=C1O)CCC2=CC=CC=C2
生化/生理作用
Inactive analog of the ATF6α-selective activator AA147.
RP22 is a AA147 analog with no ATF6α-activating potency. RP22 is the recommended inactive control for AA147 in probing ATF6α signaling-mediated unfolded protein response (UPR).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
Heike Kroeger et al.
Science signaling, 11(517) (2018-02-15)
ATF6 encodes a transcription factor that is anchored in the endoplasmic reticulum (ER) and activated during the unfolded protein response (UPR) to protect cells from ER stress. Deletion of the isoform activating transcription factor 6α (ATF6α) and its paralog ATF6β
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