SML2666
Diflapolin
≥98% (HPLC)
别名:
N-[4-(2-Benzothiazolylmethoxy)-2-methylphenyl]-N′-(3,4-dichlorophenyl)-urea, N-[4-(Benzothiazol-2-ylmethoxy)-2-methylphenyl]-N′-(3,4-dichlorophenyl)urea
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NC1=CC=C(Cl)C(Cl)=C1)NC2=C(C)C=C(OCC3=NC4=CC=CC=C4S3)C=C2
InChI
1S/C22H17Cl2N3O2S/c1-13-10-15(29-12-21-26-19-4-2-3-5-20(19)30-21)7-9-18(13)27-22(28)25-14-6-8-16(23)17(24)11-14/h2-11H,12H2,1H3,(H2,25,27,28)
InChI key
FGXLEECGXSDIMM-UHFFFAOYSA-N
Biochem/physiol Actions
Diflapolin is a bioavailable, highly potent and highly selective dual FLAP/sEH (5-LO-activating protein/ soluble epoxide hydrolase) inhibitor that suppresses leukotriene formation and increases epoxyeicosatrienoic acids levels. Diflapolin exhibit potent anti-inflammatory activities in mice models.
bioavailable, highly potent and highly selective dual FLAP/sEH (5-LO-activating protein/ soluble epoxide hydrolase) inhibitor
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable