SML3670
Raltegravir
≥98% (HPLC), HIV-1 integrase inhibitor , powder
别名:
MK 0518, MK-0518, MK0518, N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C20H21FN6O5
化学文摘社编号:
分子量:
444.42
UNSPSC Code:
51111800
NACRES:
NA.25
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
Raltegravir, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
Fc1ccc(cc1)CNC(=O)C2N=C(N(C(=O)C2=O)C)C(NC(=O)c3nnc([o]3)C)(C)C
InChI
1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,13H,9H2,1-4H3,(H,22,29)(H,24,30)
InChI key
DDGPCENTWMZXFO-UHFFFAOYSA-N
Biochem/physiol Actions
Orally active, potent and selective HIV type-1 (HIV-1) integrase inhibitor in cultures and in vivo.
Raltegravir (MK-0518) is an orally active, potent and selective HIV type-1 (HIV-1) integrase inhibitor (IC50 = 2-7 nM; ineffctive against HIV-1 reverse transcriptase or protease) that prevents HIV-1 cellular replication by blocking viral cDNA integration into host genome in cultures (IC50 = 19 nM & 33 nM in the presence of 10% fetal bovine serum or 50% human serum) and in vivo.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable