SML3810
p-Nitrobenzyl mesylate
≥98% (HPLC), alkylating reagent, powder
别名:
4-Nitro-benzenemethanol Methanesulfonate, 4-Nitrobenzyl Mesylate, PNBM
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关于此项目
经验公式（希尔记法）:
C8H9NO5S
化学文摘社编号:
分子量:
231.23
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
产品名称
p-Nitrobenzyl mesylate, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
p-Nitrobenzyl mesylate (PNBM) is a thiol-specific alkylating reagent for direct kinase substrate identification. p-Nitrobenzyl mesylate (PNBM) alkylates thiophosphorylated proteins to form thiophosphate ester epitopes that can be detected by thiophosphate-ester-specific antibody by immunoblotting, immunoprecipitation or immunoaffinity purification.
thiol-specific alkylating reagent for direct kinase substrate identification
Disclaimer
Hygroscopic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction
Cell Metabolism, 22(5), 907-921 (2015)
PKC?/? inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
Molecular Cell, 81(21), 4509-4526 (2021)
A semisynthetic epitope for kinase substrates
Nature Methods, 4(6), 511-516 (2007)
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