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SRE0022

β-葡萄糖醛酸酶

Name: β-葡萄糖醛酸酶
Brand: SIGMA

Chromatographically purified, lyophilized powder, β-glucuronidase ≥20,000,000 units/g protein

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关于此项目

UNSPSC Code:

12352204

NACRES:

NA.54

EC Number:

232-606-8

MDL number:

MFCD00130629

EC 号:

3.1.2.31 (BRENDA, IUBMB)

Biological source:

abalone

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属性

biological source

abalone

form

lyophilized powder

β-glucuronidase activity

≥20,000,000 units/g protein

secondary activity

≤4,000,000 units/g protein sulfatase

composition

protein, 10-40%

storage temp.

−20°C

说明

Application

β-Glucuronidase from abalone has been used in enzyme treatment to know the effect of osmotic shock, enzymatic incubation, pulsed electric field, and high shear homogenization on the release of water-soluble proteins and carbohydrates from the green alga Ulva lactuca.

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关于Sigma R&D生成的最新应用数据以便使用不同来源的酶优化不同药物类别的水解，并使用色谱纯化酶降低酯酶活性的影响，导致6-MAM转化为吗啡

Biochem/physiol Actions

β-Glucuronidase (GUSB) is a lysosomal enzyme. It degrades glucuronate-containing glycosaminoglycan. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Deficiency of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.

Physical form

Supplied as a lyophilized powder containing Trizma^® and L-arginine

Other Notes

在37℃，pH 3.8（30分钟检测）条件下，一个Sigma或改良的Fishman单位可每小时从酚酞葡糖苷酸中释放1.0 μg酚酞。

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS08

signalword

Danger

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

hcodes

H334

pcodes

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

wgk

WGK 1

法规信息

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商品

Evaluation of Different Enzymes on Hydrolysis Efficiencies of Glucuronide Drug Metabolites in Urine

β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.

Biorefinery of the macroalgae Ulva lactuca: extraction of proteins and carbohydrates by mild disintegration

Postma P R, et al.

Journal of Applied Phycology, 1-13 (2018)

Evaluation of abalone beta-glucuronidase substitution in current urine hydrolysis procedures

Malik W B, et al.

Journal of Analytical Toxicology, 38(3), 171-176 (2014)

Biorefinery of the macroalgae Ulva lactuca: extraction of proteins and carbohydrates by mild disintegration.

P R Postma et al.

Journal of applied phycology, 30(2), 1281-1293 (2018-05-15)

The effect of osmotic shock, enzymatic incubation, pulsed electric field, and high shear homogenization on the release of water-soluble proteins and carbohydrates from the green alga Ulva lactuca was investigated in this screening study. For osmotic shock, both temperature and

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全球贸易项目编号

货号	GTIN
SRE0022-2MU	04061832844909
SRE0022-1MU	04061826694442
SRE0022-500KU	04061832844916