SRP0337
Tyk2 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)
别名:
JTK1, tyrosine kinase 2
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352204
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Concentration:
0.18 mg/mL
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
38 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
0.18 mg/mL
technique(s)
activity assay: suitable, inhibition assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... TYK2(7297)
General description
Human Tyk2 (Tyrosine Kinase 2, also known as JTK1), (GenBank Accession No. NM_003331), amino acids 871-1187 (end) with N-terminal His-tag, MW=38 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Repr. 1B
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Partanen J, et al.
Proceedings of the National Academy of Sciences of the USA, 87, 8913-8917 (1991)
P Domanski et al.
FEBS letters, 374(3), 317-322 (1995-11-06)
The Jak kinases and Stat transcription factors play a major role in signaling of various cytokines including IFN alpha. In this report we show a ligand-independent interaction between Tyk-2 and Jak-1 kinases. We also demonstrate that the Tyk-2 kinase forms
I Firmbach-Kraft et al.
Oncogene, 5(9), 1329-1336 (1990-09-01)
We previously identified a novel protein tyrosine kinase gene, tyk2, by screening a human lymphoid cDNA library with a tyrosine kinase domain specific c-fms restriction fragment under low stringency hybridization conditions. We have now isolated and sequenced a full length
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