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Merck
CN

SRP4593

gAcrp30/Adiponectin from rat

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

别名:

Acrp30, Adipocyte-specific protein AdipoQ, Adipolean, Apm-1, adipoQ, adiponectin

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352200
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biological source

rat

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized

potency

<1-3 μg/mL

mol wt

~16.6 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

General description

Rat gAcrp30 (amp-1) is a 16.6 kDa protein that corresponds to the C-terminal globular domain of adiponectin (amp-1). gAcrp30/Adipolean is expressed and secreted exclusively by adipose tissue. This protein possesses unique pharmacological properties for regulation of body weight and lipid metabolism. It is a key component in controlling energy homeostasis. Recently, gAcrp30/Adipolean has been shown to inhibit the proliferation of myelomonocytic progenitors. The Recombinant rat gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.

Physical form

Sterile filtered and Lyophilized without additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of <0.3 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

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Zhongyuan Wen et al.
Obesity (Silver Spring, Md.), 28(10), 1932-1940 (2020-08-28)
This study aimed to elucidate the mechanism by which hypertrophic adipocytes regulate insulin signaling in cardiac myocytes. Palmitate was used to induce hypertrophic 3T3-L1 adipocytes. Exosomes were purified from normal control or hypertrophic 3T3-L1 adipocyte-associated conditioned medium. Exosome-exposed neonatal rat

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