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SRP4667

GDF-5 human

Name: GDF-5 human
Brand: SIGMA

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

别名:

CDMP-1, Cartilage-Derived Morphogenetic Protein-1, Cartilage-derived morphogenetic protein-1, LAP4, Radotermin, SYNS2

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关于此项目

NACRES:

NA.32

UNSPSC Code:

12352202

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属性

biological source

human

recombinant

expressed in E. coli

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

form

lyophilized

mol wt

~26.8 kDa

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

P43026

UniProt accession no.

P43026

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GDF5(8200)

说明

General description

GDF-5 acts as an inhibitor of nerve tissue growth. It is produced as a homodimer, non-glycosylated polypeptide chain containing 2 X 117 amino acids with a molecular weight of 26.8 kDa. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro- Leu- Thr and added the Lys.

Physical form

Sterile filtered and Lyophilized without additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 20 Mm HOAc to a concentration of 0.1 to 1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

50967

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CORR® ORS Richard A. Brand Award for Outstanding Orthopaedic Research: Engineering flexor tendon repair with lubricant, cells, and cytokines in a canine model.

Chunfeng Zhao et al.

Clinical orthopaedics and related research, 472(9), 2569-2578 (2014-06-08)

Adhesions and poor healing are complications of flexor tendon repair. The purpose of this study was to investigate a tissue engineering approach to improve functional outcomes after flexor tendon repair in a canine model. Flexor digitorum profundus tendons were lacerated

Dynamic profile and adipogenic role of growth differentiation factor 5 (GDF5) in the differentiation of 3T3-L1 preadipocytes.

Zhou Pei et al.

Archives of biochemistry and biophysics, 560, 27-35 (2014-08-01)

Adipocyte differentiation is key to determining the number of adipocytes during the development of obesity. Recent studies have shown that growth differentiation factor-5 (GDF5) promotes brown adipogenesis, however its role in white adipogenesis is still uncertain. The aim of the

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货号	GTIN
SRP4667-50UG	04061837227240