biological source
human
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized
potency
150-300 ng/mL
mol wt
~7.9 kDa
packaging
pkg of 25 μg
impurities
endotoxin, tested
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... EPGN(255324)
General description
The precursor EPGN (epigen) is a transmembrane glycoprotein and is widely expressed in human tissues. The precursor is cleaved to give a soluble EGF (epidermal growth factor)-like domain.
Recombinant Human epigen, produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.
Recombinant Human epigen, produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.
Biochem/physiol Actions
EPGN (epigen) is a ligand for EGFR (epidermal growth factor receptor). EPGN (epigen) belongs to the EGF family and enhances proliferation in keratinocytes.
Physical form
EPGN was lyophilized from 20 mM PBS buffer pH-7.4 containing 130 mM sodium chloride.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile d-H2O not less than 100 μg/ml. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
法规信息
新产品
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Kochupurakkal BS, et al.
The Journal of Biological Chemistry, 280, 8503-8503 (2005)
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