form
buffered aqueous glycerol solution
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥70% (SDS-PAGE)
mol wt
~110 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KAT7(11143)
General description
KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells. KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4.
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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The Journal of biological chemistry, 274(33), 23027-23034 (1999-08-07)
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