biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
liquid
mol wt
97.0 kDa
packaging
pkg of 25 μg
concentration
~2.0 mg/mL
impurities
Endotoxin, tested
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UBP5(8078)
General description
Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.
Physical form
Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 Mmn ?-mercaptoethanol, pH 7.5.
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