生物来源
human
重组
expressed in E. coli
方案
≥95% (SDS-PAGE)
表单
liquid
分子量
24.8 kDa (223 aa)
包装
pkg of 100 μg
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... UCHL1(7345)
一般描述
PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson′s disease susceptibility. Recombinant PGP9.5 protein was expressed in E.coli and purified by using conventional chromatography techniques.
外形
1 mg/mL solution in In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA.
制备说明
Centrifuge the vial prior to opening.
其他说明
MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
法规信息
新产品
此项目有
Vikram Puvenna et al.
PloS one, 9(5), e96296-e96296 (2014-05-09)
The impact of sub-concussive head hits (sub-CHIs) has been recently investigated in American football players, a population at risk for varying degrees of post-traumatic sequelae. Results show how sub-CHIs in athletes translate in serum as the appearance of reporters of
Ewa Matuszczak et al.
Advances in medical sciences, 62(1), 83-86 (2017-02-15)
The study aims to determinate concentrations of ubiquitin C-terminal hydrolase 1 (UCHL1), which hydrolyzes amino acids from ubiquitin and cleave di-ubiquitins, in serum of children after thermal injury. 42 children scalded by hot water, managed at the Department of Pediatric
Roshan Kumar et al.
Scientific reports, 7, 44558-44558 (2017-03-17)
Ubiquitin C-terminal Hydrolase-1 (UCHL1) is a deubiquitinating enzyme, which plays a key role in Parkinson's disease (PD). It is one of the most important proteins, which constitute Lewy body in PD patient. However, how this well folded highly soluble protein
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