SRP6109
α-烯醇化酶 人
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
别名:
α-烯醇化酶, 2-磷酸-D-甘油酸水解酶, ENO1, 烯醇酶1, 非神经烯醇酶
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关于此项目
Form:
liquid
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
47.1 kDa (434 aa, 1-434 aa)
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
liquid
mol wt
47.1 kDa (434 aa, 1-434 aa)
packaging
pkg of 100 μg
technique(s)
activity assay: suitable
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... ENO1(2023)
General description
αα-烯醇化酶，又称烯醇化酶1，是三种烯醇化酶同功酶之一，是一种在大多数组织中表达的糖酵解酶。它主要在胚胎发育的早期表达。该酶由两个分别含有433个氨基酸的亚基组成。每个亚基的摩尔质量为47 kDa。该二聚体在镁存在下稳定。
α-烯醇化酶由定位于人类染色体1p36.3-p36.2的基因编码。
Application
α人-烯醇化酶已用于体外激酶活性测定。
Biochem/physiol Actions
α-烯醇化酶催化2-磷酸甘油酸脱水为磷酸烯醇丙酮酸。该蛋白质在缺氧条件下的无氧代谢中发挥关键作用，在组织侵袭过程中可能作为细胞表面纤溶酶原受体。在一些乳腺癌和肺癌患者中，α-烯醇化酶的异常表达与肿瘤进展有关。′
Physical form
1 mg/mL溶于含有10%甘油和1 mM MgSO4的20 mM Tris-HCl（pH 7.5）
Preparation Note
打开样品瓶之前需离心。
Other Notes
MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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