生物来源
human
重组
expressed in human cells
方案
≥95% (SDS-PAGE)
表单
lyophilized
分子量
(17 and 27 kDa, monomer, glycosylated)
包装
pkg of 10 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... FGF4(2249)
一般描述
The FGF4 (fibroblast growth factor 4) gene is mapped to human chromosome 11q13.3. It is expressed during early embryonic development. In adults, it is strongly expressed in the testis.
生化/生理作用
FGF4 (fibroblast growth factor 4) helps in preserving the self-renewal capability of normal stem cells. The encoded protein has the ability to interact with FGFR1c (FGF receptor 1c) and FGFR2c. It also binds to FGFR3c and FGFR4, but to a lesser extent. FGFR4 is also required for cellular differentiation, morphogenesis and proliferation. It modulates proliferation and differentiation of normal stem cells, progenitor cells and cancer cells.
外形
Lyophilized from a PBS solution.
制备说明
Centrifuge the vial prior to opening.
重悬
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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