Jacalin is isolated from Jackfruit seeds and purified by affinity chromatography. It is a glycoprotein with two non-covalently bound subunits (14.6 and 17.1 kDa) and belongs to the family of galactose-binding lectins. Jacalin is preferably used in applications to isolate IgA from human serum, isolating human plasma glycoproteins and for applications in histochemistry. BioVision′s Jacalin is supplied as a white to light-yellow lyophilized powder without additives. The purity of the lectin is determined by SDS-PAGE, generating two homogeneous bands at 14 kDa and 17 kDa. Gene Bank Accession Number Q38720.

Jacalin is one of the two lectins found in jackfruit seeds. The other lectin is artocarpin. Jacalin has been used to inhibit herpes simplex virus type 2. It has been used to assess the immune status of patients infected with human immunodeficiency virus 1 (HIV1) as it exhibits mitogenic effect on human CD₄⁺T lymphocytes. It has been used to analyze 0-linked glycoproteins due to its high specificity for O-glycoside of the disaccharide Thomsen-Friedenreich antigen (Galβ1-3GalNAc).

Lyophilized without additives

Centrifuge the vial prior to opening.

Reconstitute in water.

MAYSSLLSLS VLALLFSISS ADTRKWFLAN GINQNPIGII EAAVGVSEDL LNLNGMEAKN KSQTV IVGPWGAQVS TSSNGKAFDD GAFTGIREIN LSYNKETAIG DFQVIYDLNG SPYVGQNHTS FIKGFTPVKI SLDFPSEYIV DVSGYTGKVS GYVVVRSLTF KTNKKTYGPY GVTSGTPFNL PIENGLVVGF KGSIGYWLDY FSMYLSL