biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
liquid
mol wt
24.8 kDa (225 aa, 31-232 aa + His tag)
packaging
pkg of 50 μg
concentration
1 mg/mL
impurities
<1 EU/μg endotoxin (LAL test)
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CD200(4345)
General description
CD200 is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. Recombinant human CD200 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Physical form
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Stanislava Pankratova et al.
Molecular neurobiology, 53(1), 584-594 (2014-12-17)
The CD200 ligand is expressed by a variety of cell types, including vascular endothelia, kidney glomeruli, some subsets of T and B cells, and neurons in the brain and periphery. In contrast, the receptor of CD200, CD200R, has a limited
Li-Chun Weng et al.
Journal of reproductive immunology, 138, 103090-103090 (2020-02-06)
Endometriosis (EMS) is a benign disease that is related to estrogen, immune disorders and inflammation. The purpose of this research was to determine the expression of CD200 in EMS and to clarify its role in the pathogenesis of the disease.
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