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Merck
CN

SRP6363

KLRB1 human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE)

别名:

CD161, CLEC5B, Killer cell lectin-like receptor subfamily B member 1, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352200
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥85% (SDS-PAGE)
Form:
liquid
Mol wt:
21 kDa (183 aa, 67-225 aa + His Tag)
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biological source

human

recombinant

expressed in E. coli

assay

≥85% (SDS-PAGE)

form

liquid

mol wt

21 kDa (183 aa, 67-225 aa + His Tag)

packaging

pkg of 100 μg

concentration

1 mg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KLRB1(3820)

General description

Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physical form

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Alba Llibre et al.
Journal of immunology (Baltimore, Md. : 1950), 196(5), 2085-2094 (2016-02-03)
Germinal centers (GCs) are microanatomical structures critical for the development of high-affinity Abs and B cell memory. They are organized into two zones, light and dark, with coordinated roles, controlled by local signaling. The innate lectin-like transcript 1 (LLT1) is



全球贸易项目编号

货号GTIN
SRP6363-100UG04061837252303