SRP6372
胞苷脱氨酶 人
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
别名:
CDA, CDD, 胞嘧啶核苷脱氨酶, 胞苷氨基水解酶
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NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Concentration:
0.5 mg/mL
General description
胞苷脱氨酶（CDA）是一种清除外源和内源性胞苷和2′-脱氧胞苷的酶，可用于UMP合成。该蛋白是负责维持细胞嘧啶池的几种脱氨酶之一。CDA还可催化化学疗法胞嘧啶核苷类似物（如阿拉伯呋喃糖基胞苷（Ara-C）和5-氮胞苷）的脱氨基反应，从而导致其细胞毒性和抗肿瘤功能丧失。
Biochem/physiol Actions
胞嘧啶脱氨酶（CDA）主要在粒细胞中表达，可以形成同源四聚体。在N端与His标签融合的重组人CDA蛋白，其在大肠杆菌中表达并通过常规色谱进行纯化。
Physical form
0.5 mg/mL，溶于含有100 mM NaCl、1 mM DTT、2 mM EDTA和40％甘油的20 mM Tris-HCl缓冲液（pH 8.0）中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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