生物来源
human
重组
expressed in HEK 293 cells
标签
6-His tagged (C-terminus)
方案
≥95% (SDS-PAGE)
表单
lyophilized
分子量
calculated mol wt 45.2 kDa
observed mol wt 45-55 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 20 is the predicted N-terminal.)
包装
pkg of 10 μg
pkg of 50 μg
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... SERPINF1(5176)
一般描述
Serpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.
外形
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
制备说明
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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