SRP6549
碱性磷酸酶 来源于小牛肠
≥98% (SDS-PAGE)
别名:
ALP, ALP-1, ALPP, ALPPL, ALPPL2, PALP, PLAP, PLAP-1
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关于此项目
EC Number:
232-631-4
UNSPSC Code:
12352205
Biological source:
bovine (calf) intestine
Assay:
≥98% (SDS-PAGE)
Form:
freeze-dried protein glass
Impurities:
3000-6,000 EU/μg endotoxin (LAL test)
biological source
bovine (calf) intestine
assay
≥98% (SDS-PAGE)
form
freeze-dried protein glass
packaging
pkg of 1 mg, pkg of 10 μg, pkg of 50 μg
impurities
3000-6,000 EU/μg endotoxin (LAL test)
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
bovine (calf) ... ALPL(280994)
General description
碱性磷酸酶（ALP）是一种水解酶。小牛肠粘膜中的碱性磷酸酶是高活性形式。小牛肠碱性磷酸酶是二聚体糖蛋白，分子量约为 140kDa。
Application
来自小牛肠的碱性磷酸酶已被用作碱性磷酸酶测定的标准。
Biochem/physiol Actions
碱性磷酸酶（ALP）负责从许多类型的分子（例如核苷酸、蛋白质和生物碱）中除去 5-和 3-位的磷酸基团。它还可以通过催化脂质 A 结构的去磷酸化来修饰脂多糖，从而降低脂多糖的毒性。
Physical form
冻干品，无任何添加剂。
Preparation Note
重悬于蒸馏水或稀释缓冲液中。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
此项目有
Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota.
Cell host & microbe, 2, 371-382 (2007)
Quantitation of surface coverage of oligonucleotides bound to chip surfaces: a fluorescence-based approach using alkaline phosphatase digestion.
Pal S
Lab on a chip, 8, 1332-1341 (2008)
Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity.
Addison WN
The Journal of Biological Chemistry, 282, 15872-15883 (2007)
Affinity-chromatography purification of alkaline phosphatase from calf intestine.
Brenna O
The Biochemical Journal, 151, 291-296 (1975)
Intestinal alkaline phosphatase. Physical properties and quaternary structure.
M Fosset et al.
Biochemistry, 13(9), 1783-1788 (1974-04-23)
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