生物来源
human
重组
expressed in E. coli
方案
≥90% (SDS-PAGE)
表单
lyophilized
分子量
39.9 kDa
包装
pkg of 1 mg
pkg of 10 μg
pkg of 50 μg
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... WNT2(7472)
生化/生理作用
Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers.
外形
Lyophilized without additives.
制备说明
Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Wnt signal transduction pathways
Yuko Komiya
Organogenesis, 4(2), 68-75 (2008)
Overexpression of Wnt-2 in colorectal cancers.
Park JK
Neoplasma, 56(2), 119-123 (2009)
Wnt2 is a direct downstream target of GATA6 during early cardiogenesis
Alexander A
Mechanisms of Development, 123, 297-311 (2006)
Wnt2 as a new therapeutic target in malignant pleural mesothelioma
Julien Mazieres
International Journal of Cancer. Journal International Du Cancer (2005)
Steven Hyman
Autism: The Science of Mental Health (2013)
商品
Role of growth factors in stem cell differentiation and various growth factors for your research at sigmaaldrich.com
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