生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
种属反应性
human
技术
neutralization: suitable
western blot: suitable
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TGFB1(7040)
一般描述
Transforming Growth Factor-β1 (TGF β1) is a multifunctional protein that can stimulate or inhibit cellular proliferation. Mesenchymal origin cells are stimulated by TGF β1 while T and B lymphocytes, keratinocytes, hepatocytes and epithelial cells are inhibited by TGF β1. It facilitates in tissue growth and differentiation by participating in myogenesis, osteogenesis, adipogenesis, chondrogenesis, epithelial cell differentiation and immune cell function. Anti-Transforming Growth Factor-β1 antibody can be used in neutralization assay. Chicken anti-TGF β1 reacts specifically with recombinant human TGF-β1 or TGF-β1.2.
免疫原
Recombinant human TGF-β1 expressed in CHO cells.
应用
Anti-Transforming Growth Factor-β1 antibody can be used in western blotting.
生化/生理作用
The antibody will neutralize the biological activity of recombinant human TGF-β1 and porcine TGF-β1.2.
外形
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
G D Shipley et al.
Cancer research, 46(4 Pt 2), 2068-2071 (1986-04-01)
Type beta transforming growth factor-growth inhibitor (TGF beta/GI) causes normal human prokeratinocytes to arrest growth predominantly in the G1 phase of the cell cycle within 48 h after log phase cultures are exposed to the factor in serum-free medium. The
J H Kehrl et al.
The Journal of experimental medicine, 163(5), 1037-1050 (1986-05-01)
This study examines the potential role of transforming growth factor beta (TGF-beta) in the regulation of human T lymphocyte proliferation, and proposes that TGF-beta is an important autoregulatory lymphokine that limits T lymphocyte clonal expansion, and that TGF-beta production by
S Cheifetz et al.
Cell, 48(3), 409-415 (1987-02-13)
A new homodimer form of transforming growth factor-beta (TGF-beta), TGF-beta 2, has been identified in porcine blood platelets. TGF-beta 2 is homologous to ordinary TGF-beta (TGF-beta 1), which is also present in platelets. TGF-beta 1.2, a heterodimer containing one TGF-beta
I Hayashi et al.
Journal of cellular physiology, 125(1), 82-90 (1985-10-01)
Primary monolayer cultures of adult rat hepatocytes can be induced to undergo DNA synthesis in serum-free medium in the presence of insulin, glucagon, and epidermal growth factor (three factors). We have found that hepatocyte DNA synthesis is affected not only
C B Childs et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(17), 5312-5316 (1982-09-01)
High concentrations of fetal bovine serum induced colony formation in soft agar by anchorage-dependent, nontransformed mouse AKR-2B and rat NRK cells. The colony-stimulating activity in fetal bovine serum was precipitated by 45% saturated ammonium sulfate and migrated in molecular sieve
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