InChI key
OTXNTMVVOOBZCV-WAZJVIJMSA-N
InChI
1S/C28H42O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1
SMILES string
C/C(CC/C=C(C)/CCC=C(C)C)=C\CC[C@@]1(C)OC2=C(C)C(C)=C(O)C=C2CC1
biological source
palm oil
assay
≥80% (GC)
storage temp.
−20°C
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Biochem/physiol Actions
Tocotrienols are widely utilized for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. In addition to its antioxidant properties γ-tocotrienol has been shown to inhibit the NF-κB activation pathway. γ-tocotrienol also acts as an inhibitor of HMG-CoA, the rate limiting enzyme in cholesterol biosynthesis.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Bilal S Abuasal et al.
Lipids, 47(5), 461-469 (2012-01-25)
γ-Tocotrienol (γ-T3), a member of the vitamin E family, has been reported to possess an anticancer activity. γ-T3 is a lipophilic compound with low oral bioavailability. Previous studies showed that γ-T3 has low intestinal permeability. Thus, we have hypothesized that
[Chloroplast prenylated lipids in response to stress in plants].
Renata Szymańska
Postepy biochemii, 58(4), 372-376 (2012-01-01)
Maaike Berbée et al.
Current opinion in supportive and palliative care, 6(1), 54-59 (2012-01-10)
To give an overview of promising novel agents under development for the prevention and reduction of gastrointestinal radiation injury. Currently, several novel agents are being tested as drugs to prevent or reduce gastrointestinal radiation injury. These drugs may not only
Kanjoormana A Manu et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 18(8), 2220-2229 (2012-02-22)
Because of poor prognosis and development of resistance against chemotherapeutic drugs, the existing treatment modalities for gastric cancer are ineffective. Hence, novel agents that are safe and effective are urgently needed. Whether γ-tocotrienol can sensitize gastric cancer to capecitabine in
Su Liang et al.
Biomedical chromatography : BMC, 27(1), 58-66 (2012-04-24)
γ-Tocotrienol has attracted much attention owing to its multiple health benefits. This study developed and validated a simple, specific, sensitive and reliable LC/MS/MS method to analyze γ-tocotrienol in rat plasma. Plasma samples (50 μL) were extracted with internal standard solution (25 ng/mL
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