T1019
(±)-Thiopental
别名:
5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, Pentothal
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关于此项目
经验公式（希尔记法）:
C11H18N2O2S
化学文摘社编号:
分子量:
242.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-984-3
MDL number:
InChI key
IUJDSEJGGMCXSG-UHFFFAOYSA-N
InChI
1S/C11H18N2O2S/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)
SMILES string
CCCC(C)C1(CC)C(=O)NC(=S)NC1=O
drug control
USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
ethanol: complete 50 mg/mL
originator
Abbott
Quality Level
Gene Information
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Application
(±)-Thiopental was used to transiently anesthetize rats for in vivo NMR spectroscopy.
Biochem/physiol Actions
Thiopental is an anesthetic that decreases cerebral metabolic rate without altering the blood flow or oxygen consumption.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
B M Jucker et al.
The Journal of biological chemistry, 272(16), 10464-10473 (1997-04-18)
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Cerebral circulation and metabolism during thiopental anesthesia and hyper-ventilation in man.
E C PIERCE et al.
The Journal of clinical investigation, 41, 1664-1671 (1962-08-01)
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