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T1019

(±)-Thiopental

Name: (±)-Thiopental
Brand: SIGMA

别名:

5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, Pentothal

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关于此项目

经验公式（希尔记法）:

C₁₁H₁₈N₂O₂S

化学文摘社编号:

76-75-5

分子量:

242.34

NACRES:

NA.77

PubChem Substance ID:

24899925

UNSPSC Code:

41116107

EC Number:

200-984-3

MDL number:

MFCD00057564

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属性

drug control

USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada

Quality Segment

200

solubility

ethanol: complete 50 mg/mL

originator

Abbott

SMILES string

CCCC(C)C1(CC)C(=O)NC(=S)NC1=O

InChI

1S/C11H18N2O2S/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key

IUJDSEJGGMCXSG-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

说明

Application

(±)-Thiopental was used to transiently anesthetize rats for in vivo NMR spectroscopy.

Biochem/physiol Actions

Thiopental is an anesthetic that decreases cerebral metabolic rate without altering the blood flow or oxygen consumption.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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