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Merck
CN

T2022

Thyroxine-Binding Globulin 来源于人类血浆

buffered aqueous solution

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UNSPSC Code:
51111800
MDL number:
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form

buffered aqueous solution

impurities

<0.1 mol/mol protein T4

capacity

≥0.7 mol/mol, protein binding capacity (T4)

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... SERPINA7(6906)

Physical form

Solution in 0.05 M Tris, pH 8.6, containing 0.25 M NaCl, 0.3 M glycine, and 0.1% sodium azide

Preparation Note

Glycoprotein (54 kDa) produced in the liver and is the primary carrier of thyroxine and triiodothyronine in serum.

Analysis Note

Protein determined by Lowry.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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O E Janssen et al.
The Journal of biological chemistry, 267(20), 13998-14004 (1992-07-15)
Thyroxine-binding globulin (TBG) is a glycoprotein that transports thyroid hormones in blood. Of two naturally occurring variants in man that harbor single proline substitutions (TBG-CD5 and TBG-Montreal), only TBG-CD5 manifests as complete TBG deficiency. In order to determine the pathophysiology

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