T5455
TAT-JBD trifluoroacetate salt
≥95% (HPLC)
别名:
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH2 trifluoroacetate, TAT-TI-JIP153–163 trifluoroacetate, YGRKKRRQRRRRPKRPTTLNLF trifluoroacetate
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C125H220N52O27 · xC2HF3O2
分子量:
2883.42 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
assay
≥95% (HPLC)
form
lyophilized solid
storage condition
desiccated, protect from light
color
white
solubility
H2O: >1 mg/mL
storage temp.
−20°C
Biochem/physiol Actions
TAT-JBD can decrease 1-methyl-4-phenylpyridinium ion (MPP(+))-induced caspase-9 stimulation in rat cells1.
TAT-JBD is a cell-permeable JNK inhibitor.
Features and Benefits
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
TAT-JBD trifluoroacetate salt is soluble in water at a concentration that is greater than 1 mg/ml.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Stéphanie Pain et al.
Toxicology, 243(1-2), 124-137 (2007-11-27)
Many studies showed that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) which was widely used to produce Parkinson's disease (PD)-like models in animals can elicit apoptosis with increase of caspase activity via its neurotoxic metabolite 1-methyl-4-phenylpyridinium ion (MPP(+)). Another pathway shown in MPTP-mediated nigrostriatal dopaminergic
商品
The mitogen-activated protein kinase (MAPK) family consists of stress-activated (SAPK) and MAPKs. Learn about their network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli.
丝裂原活化蛋白激酶(MAPK)家族由应激激活(SAPK)和丝裂原活化(MAPK)的蛋白激酶组成。了解它们介导细胞多种刺激反应的信号转导级联网络。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持