T5455
TAT-JBD trifluoroacetate salt
≥95% (HPLC)
别名:
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH2 trifluoroacetate, TAT-TI-JIP153–163 trifluoroacetate, YGRKKRRQRRRRPKRPTTLNLF trifluoroacetate
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关于此项目
经验公式（希尔记法）:
C125H220N52O27 · xC2HF3O2
分子量:
2883.42 (free base basis)
UNSPSC代码:
12352200
NACRES:
NA.77
方案
≥95% (HPLC)
表单
lyophilized solid
储存条件
desiccated
protect from light
颜色
white
溶解性
H2O: >1 mg/mL
储存温度
−20°C
Amino Acid Sequence
Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH2
生化/生理作用
TAT-JBD can decrease 1-methyl-4-phenylpyridinium ion (MPP(+))-induced caspase-9 stimulation in rat cells1.
TAT-JBD is a cell-permeable JNK inhibitor.
特点和优势
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
制备说明
TAT-JBD trifluoroacetate salt is soluble in water at a concentration that is greater than 1 mg/ml.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Stéphanie Pain et al.
Toxicology, 243(1-2), 124-137 (2007-11-27)
Many studies showed that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) which was widely used to produce Parkinson's disease (PD)-like models in animals can elicit apoptosis with increase of caspase activity via its neurotoxic metabolite 1-methyl-4-phenylpyridinium ion (MPP(+)). Another pathway shown in MPTP-mediated nigrostriatal dopaminergic
商品
The mitogen-activated protein kinase (MAPK) family consists of stress-activated (SAPK) and MAPKs. Learn about their network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli.
丝裂原活化蛋白激酶(MAPK)家族由应激激活(SAPK)和丝裂原活化(MAPK)的蛋白激酶组成。了解它们介导细胞多种刺激反应的信号转导级联网络。
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