T5943
Tyrphostin AG 1007
≥98%, solid
生化/生理作用
Tyrphostin AG 1007 is known to function as a receptor tyrosine kinase inhibitor. It has been reported that replacement of oxygen in the carbonyl group of AG-1007 significantly increased the inhibition of tyrosine autophosphorylation of IGF-1R1.
制备说明
Tyrphostin AG 1007 is soluble in DMSO and acetone.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
G Blum et al.
Biochemistry, 39(51), 15705-15712 (2000-12-22)
IGF-1 and its receptor play a pivotal role in many cancers, and therefore, IGF-1R is an attractive target for the design of inhibitors. In this communication, we report on a number of lead compounds for inhibitors of the isolated IGF-1R
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