Tau is a microtubule-associated phosphoprotein that is present in the axons of nerve cells. It stabilizes microtubules and mediates the polymerization of tubulin. Phosphorylation of Tau regulates its cellular functions. Hyperphosphorylation of Tau has been linked to neurodegenerative disorders such as Alzheimer′s disease . Anti-phospho-Tau (pSer⁴⁰⁴) antibody specifically reacts with Tau (pSer⁴⁰⁴) (45-68 kDa) in humans, mice and rats.

chemically synthesized phosphopeptide derived from the region of human tau that contains serine⁴⁰⁴.

Anti-phospho-Tau (pSer⁴⁰⁴) antibody may be used in western blot (1:1000), immunoblot (1:1000) and immunohistochemistry.

Solution in Dulbecco′s phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

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