T7556
Tropine 2-(phenylthio)butanoate oxalate salt
≥98%
别名:
SM32
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关于此项目
经验公式（希尔记法）:
C18H25NO2S · C2H2O4
化学文摘社编号:
分子量:
409.50
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
方案
≥98%
储存温度
2-8°C
SMILES字符串
OC(=O)C(O)=O.CCC(Sc1ccccc1)C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C
InChI
1S/C18H25NO2S.C2H2O4/c1-3-17(22-16-7-5-4-6-8-16)18(20)21-15-11-13-9-10-14(12-15)19(13)2;3-1(4)2(5)6/h4-8,13-15,17H,3,9-12H2,1-2H3;(H,3,4)(H,5,6)/t13-,14+,15+,17?;
InChI key
DBBVWGGNICLTMF-PPUXJDFUSA-N
生化/生理作用
Potent analgesic. Causes increased release of acetylcholine at central muscarinic synapses.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
F Gualtieri et al.
Journal of medicinal chemistry, 37(11), 1704-1711 (1994-05-27)
Previous studies have shown that (R)-(+)-hyoscyamine has analgesic activity as a consequence of increased ACh release following antagonism of central muscarinic autoreceptors. Since the enhancement of central cholinergic transmission could be beneficial for cognitive disorders, we manipulated (R)-(+)-hyoscyamine, synthesizing several
Dimitra Aravani et al.
Apoptosis : an international journal on programmed cell death, 25(9-10), 648-662 (2020-07-07)
Vascular smooth muscle cells (VSMCs) are the main structural cell of blood vessels, and VSMC apoptosis occurs in vascular disease, after injury, and in vessel remodeling during development. Although VSMC apoptosis is viewed as silent, recent studies show that apoptotic
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